Lipophilic tea polyphenols (LTP) were prepared by catalytic esterifieation of green tea polyphenols (GRIP) with hexadeeanoyl chloride. A novel long-chain aeyl-derivative of epigalloeateehin-3-o-gallate(EGCG) was first isolated from purification of LTP by high-speed eountereurrent ehromatography (HSCCC)using a solvent system composed of n-hexane-ethyl acetate-methanol-water ( 1 : 1 : 1 : 1, v/v) . The moleeularstructure of the acyl-derivative, Epigallocatechin-3-O-gallate-4"-O-hexadeeanate , was elucidated by meansof elemental analysis, IR, 1H-NMR and MS spectra.

完成机构：[1]CatalysisInstitute,ZhejiangUniversity,Hangzhou310028,China [2]MedicalCollegeofWertzhou,Wertzhou325000,China